Table of Contents

Research articles

2017

  1. Zhe Guan, Tiantian Cai, Zhongmin Liu, Yunfeng Dou, Xuesong Hu, Peng Zhang, Xin Sun, Hongwei Li, Yao Kuang, Qiran Zhai, Hao Ruan, Xuanxuan Li, Zeyang Li, Qihui Zhu, Jingeng Mai, Qining Wang, Luhua Lai, Jianguo Ji, Haiguang Liu, Bin Xia, Taijiao Jiang, Shu-Jin Luo, Hong-Wei Wang, Can Xie. Origin of the Reflectin Gene and Hierarchical Assembly of Its Protein. Current Biology, 27, 2833-2842. (2017) http://www.sciencedirect.com/science/article/pii/S096098221730965X
  2. Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, Zhao S, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ. Crystal structures of agonist-bound human cannabinoid receptor CB1. Nature 547, 468–471 (2017) https://www.nature.com/nature/journal/v547/n7664/full/nature23272.htm
  3. Na Song, …, Haiguang Liu*, SHREC'17 Track: Protein Shape Retrieval, in Eurographics Workshop on 3D Object Retrieval, editor Ioannis Pratikakis, Florent Dupont, Maks Ovsjanikov. The Eurographics Association. (2017) http://dx.doi.org/10.2312/3dor.20171055 Download PDF version.
  4. Hongxiao Wang, Haiguang Liu. Determining complex structures using docking method with single particle scattering data. Front. Mol. Biosci. 4:23. http://dx.doi.org/10.3389/fmolb.2017.00023 (2017)
  5. Xuanxuan Li,…Haiguang Liu*, Diffraction data of coreshell nanoparticles from an X-ray free electron laser, Scientific Data, 4:170048. (2017) http://dx.doi.org/10.1038/sdata.2017.48
  6. Ting Wang*, Yang Wang, Leihan Tang, Yong Duan*, Haiguang Liu*, 7×7 RMSD matrix: A new method for quantitative comparison of the transmembrane domain structures in the G-protein coupled receptors. J. of Structural Biology (2017) http://dx.doi.org/10.1016/j.jsb.2017.02.005 Download PDF version.
  7. 黄岚青, 刘海广* “冷冻电镜单颗粒技术的发展、现状与未来”( “Application of cryo-electron microscopy in structure biology: current status and future perspectives”),《物理》46 (2), 91-99, (2017) http://doi.org/10.7693/wl20170204 PDF

2016

  1. Coherent diffraction of single Rice Dwarf Virus particles using hard X-rays at the Linac Coherent Light Source. Munke A. et al., Scientific Data 3, 160064, doi:10.1038/sdata.2016.64 (2016)
  2. XFEL data analysis for structural biology. Liu H. & J.C.H. Spence, Quantitative Biology 4: 159. doi:10.1007/s40484-016-0076-z (2016)
  3. Facilitating model reconstruction for single-particle scattering using small-angle X-ray scattering methods. Ma, S. & Liu, H. J. Appl. Cryst. 49, 665-671 (2016)

2015

  1. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Y. Kang et al., Nature 523 561–567 (2015)
  2. Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. P. Nogly et al., IUCrJ 2 168 (2015)
  3. Serial femtosecond X-ray diffraction of enveloped virus microcrystals. R. M. Lawrence et al., Structural Dynamics 2 041720 (2015)
  4. Solving protein nanocrystals by cryo-EM diffraction: Multiple scattering artifacts. G. Subramanian et al., Ultramicroscopy 148 87–93 (2015)

2014

  1. Ab-initio phasing using nanocrystal shape transforms with incomplete unit cells. H. Liu and N. A. Zatsepin and J. C. Spence IUCrJ 1 19–27 (2014)
  2. Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1. H.-H. Lee et al., IUCrJ 1 305–317 (2014)
  3. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. U. Weierstall et al., Nature communications 5 (2014)
  4. Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. C. Kupitz and S. Basu et al., Nature (2014) 513, 261
  5. The indexing ambiguity in serial femtosecond crystallography (SFX) resolved using an expectation maximization algorithm. H. Liu and J. C. Spence IUCrJ 1 393–401 (2014)

Before 2014

  1. Three-dimensional single-particle imaging using angular correlations from X-ray laser data. H. Liu and B. K. Poon and D. K. Saldin and J. C. Spence and P. H. Zwart Acta Crystallographica Section A: Foundations of Crystallography 69 365–373 (2013)
  2. Computation of fluctuation scattering profiles via three-dimensional Zernike polynomials. H. Liu and B. K. Poon and A. J. Janssen and P. H. Zwart Acta Crystallographica Section A: Foundations of Crystallography 68 561–567 (2012)
  3. Computation of small-angle scattering profiles with three-dimensional Zernike polynomials. H. Liu and R. J. Morris and A. Hexemer and S. Grandison and P. H. Zwart Acta Crystallographica Section A: Foundations of Crystallography 68 278–285 (2012)
  4. Determining pair distance distribution function from SAXS data using parametric functionals. H. Liu and P. H. Zwart Journal of structural biology 180 226–234 (2012)
  5. The Small Angle Scattering ToolBox (SASTBX): an open-source software for biomolecular small-angle scattering. H. Liu and A. Hexemer and P. Zwart Journal of Applied Crystallography 45 587–593 (2012)
  6. Effects of posttranslational modifications on the structure and dynamics of histone H3 N-terminal peptide. H. Liu and Y. Duan Biophysical journal 94 4579–4585 (2008)
  7. Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations. H. Lei and C. Wu and H. Liu and Y. Duan Proceedings of the National Academy of Sciences 104 4925 (2007)
  8. Designability and cooperative folding in a fourletter hydrophobic-polar model of proteins H. Liu and LH Tang Physical Review E 74 051918 (2006)
Thesis

The dynamics of nucleosome systems and the posttranslational modification effects: Applications of molecular dynamics simulation in structural biology H. Liu (2009)

Book Chapter

Conformational Changes in Protein Function. H. Liu and S. G. Dastidar and H. Lei and W. Zhang and M. C. Lee and Y. Duan METHODS IN MOLECULAR BIOLOGY 443 259 (2008)

Richard Feynman

“everything that is living can be understood in terms of the jiggling and wiggling of atoms”.

and now, we want to watch atoms jiggling and wiggling.

X-rays, electrons, fluorescence light, the advances of photon sciences, together with computational modeling, are making this happen.