The dynamics of nucleosome systems and the posttranslational modification effects: Applications of molecular dynamics simulation in structural biology H. Liu (2009)
Conformational Changes in Protein Function. H. Liu and S. G. Dastidar and H. Lei and W. Zhang and M. C. Lee and Y. Duan METHODS IN MOLECULAR BIOLOGY 443 259 (2008)
“everything that is living can be understood in terms of the jiggling and wiggling of atoms”.
and now, we want to watch atoms jiggling and wiggling.
X-rays, electrons, fluorescence light, the advances of photon sciences, together with computational modeling, are making this happen.